Measure ID: MIPS 275|Gastroenterology|2026 Performance Year

2026 MIPS Measure #275: Inflammatory Bowel Disease (IBD): Assessment of Hepatitis B Virus (HBV) Status Before

Percentage of patients with a diagnosis of inflammatory bowel disease (IBD) who had Hepatitis B Virus (HBV) status assessed and results interpreted prior to initiating anti-TNF (tumor necrosis factor) therapy.

ProcessGastroenterologyPatient Safety
Measure ID:MIPS 275 (Quality ID 275)
Collection:MIPS CQM
Topped Out:No
View CMS Spec ↗

Measure Specification

Eligible Population
All Patients, regardless of age during the performance period
ANDDiagnosis for inflammatory bowel disease
ANDPatient encounter during the performance period
ANDPatient initiated an anti-TNF agent
Exclusions

None

Numerator
Patients who had HBV status assessed and results interpreted prior to initiating anti-TNF therapy.
Reporting Codes

Performance Met:

G9912Hepatitis B Virus (HBV) status assessed and results interpreted prior to initiating anti-TNF (tumor necrosis factor) therapy
G8869Patient has documented immunity to hepatitis B and initiating anti-TNF therapy

Performance Not Met:

G9913Hepatitis B Virus (HBV) status not assessed and results interpreted prior to initiating anti-TNF (tumor necrosis factor) therapy, reason not otherwise specified
G9915No record of HBV results documented

○ Exceptions:

G9504Documented reason for not assessing Hepatitis B Virus (HBV) status (e.g. patient not initiating anti-TNF therapy, patient declined) prior to initiating anti-TNF therapy
VBCA Insights

Why This Measure Matters

Before you start a patient on biologic anti-TNF therapy for inflammatory bowel disease, you must screen them for hepatitis B. These powerful immune-suppressing drugs can reactivate dormant hepatitis B, causing serious liver disease. Check their HBsAG, HBcAb, or HBsAB status and document the results before the first dose. It's a straightforward safety gate that prevents a potentially life-threatening complication and should be part of every pre-biologic workup.

VBCA is a CMS-approved Qualified Clinical Data Registry (QCDR) that submits MIPS Measure 275 to the Quality Payment Program (QPP). Practices can report this measure as a MIPS Clinical Quality Measure (CQM) or through qualified registry submission.

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Specialty Measure Sets

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Clinical Rationale

Before initiating biologic anti-TNF therapy for a patient with IBD, it is essential to screen the patient for HBV, as research has documented reactivation of HBV after anti-TNF therapy. This is a patient safety measure. Opportunity for improvement: While there are a limited number of studies that investigate gaps in care for patients with IBD, the research that does exist identifies opportunities for improvement in care areas: 1) there is a lack of adherence to documentation of HBV screening, most noticeably in the use of disease-modifying anti-TNF drugs, and variations in care by practice setting, geographic region and physician specialty.

See FDA package labeling for anti-TNF biological agents — golimumab, certolizumab pegol, infliximab and adalimumab. Reactivation of hepatitis B virus has been reported in patients who are carriers of this virus and are taking TNF blocker medicines. (Kaiser T, Moessner J, McHutchison JG, Tillmann HG. Life threatening liver disease during treatment with monoclonal antibodies.

BMJ.

Clinical Recommendations

Infliximab can reactivate latent HBV. (Esteve et al. 2004).

Implementation Notes

For the purposes of MIPS implementation, this patient-process measure is submitted a minimum of once per patient for the performance period. The most advantageous quality data code will be used if the measure is submitted more than once. Telehealth

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