Measure ID: MIPS 499|Ophthalmology|2026 Performance Year

Appropriate Screening and Plan of Care for Elevated Intraocular Pressure Following

Percentage of patients who had an intravitreal or periocular corticosteroid injection (e.g., triamcinolone, preservative-free triamcinolone, dexamethasone, dexamethasone intravitreal implant, or fluocinolone intravitreal implant) who, within seven (7) weeks following the date of injection, are screened for elevated intraocular pressure (IOP) with tonometry with documented IOP ≤ 25 mm Hg for injected eye OR if the IOP was > 25 mm Hg, a plan of care was documented.

ProcessOphthalmologyGlaucoma

Last updated: January 15, 2026

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Measure Specification

Denominator (Eligible Population)

All patients regardless of age
ANDPatient encounters during the performance period
WITHOUTEncounters conducted via telehealth: M1426
ANDPatients who had an intravitreal or periocular corticosteroid injection (e.g., triamcinolone, preservative-free triamcinolone, dexamethasone, dexamethasone intravitreal implant, or fluocinolone intravitreal implant): M1324

Denominator Exclusions1

M1326Patients with a diagnosis of hypotony

Numerator

Number of patients who, within seven (7) weeks following the date of injection, are screened for elevated intraocular pressure (IOP) with tonometry with documented IOP ≤ 25 mm Hg for injected eye listed in chart OR if the IOP was > 25 mm Hg, a plan of care was documented.

Submission Codes (QDCs)

✓ Performance Met
M1322Patients seen within 7 weeks following the date of injection AND are screened for elevated intraocular pressure (IOP) with tonometry with documented IOP ≤ 25 mm Hg for injected eye
M1323Patients seen within 7 weeks following the date of injection AND are screened for elevated intraocular pressure (IOP) with tonometry with documented IOP > 25 mm Hg AND a plan of care was documented
✗ Performance Not Met
M1321Patients who were not seen within 7 weeks following the date of injection for follow up OR who did not have a documented IOP OR no plan of care documented if the IOP was > 25 mm Hg

Denominator Exceptions

M1325Denominator Exception: Patients who were not seen for reasons documented by clinician for patient or medical reasons (e.g., inadequate time for follow-up, patients who received a prior intravitreal or periocular steroid injection within the last six (6) months and had a subsequent IOP evaluation with IOP < 25mm Hg within seven (7) weeks of treatment)

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VBCA Insights

💡Why This Measure Matters

After patients receive an intravitreal or periocular corticosteroid injection (common in ophthalmology), they're at risk for steroid-induced high eye pressure (elevated IOP) which can lead to glaucoma and vision loss. This measure ensures you screen for elevated IOP with tonometry within seven weeks after injection, and if IOP is high, you document a plan to manage it (drops, laser, or other interventions). Seven to nine weeks is the peak risk window, so timely screening and intervention prevent serious vision-threatening complications.

📖Clinical Rationale

Patients treated with corticosteroid therapy are at increased risk for elevated IOP leading to steroid-induced glaucoma and their quality of life may be negatively impacted due to visual impairments. Several randomized clinical trials and a systematic review identified that IOPs typically peak around 7-9 weeks. Ensuring that appropriate monitoring is conducted to detect and treat this complication is important to prevent significant visual morbidity.

This measure encourages providers to screen and treat patients identified with an elevated IOP in a timely manner.

📝Clinical Recommendations

While current clinical guidelines do not address the need to assess for elevated IOP following corticosteroid injection, a systematic review completed by Kiddee and colleagues (Kiddee, 2013) identified that 10.9% to 79.0% of these patients will develop clinically significant IOP elevations with the large variation in incidence dependent largely on the specific steroid utilized and dose administered.

The timing of IOP elevation also varies based on the type and dose; although, the available literature consistently shows IOP peaking in the 4-8 week range following injection with higher and earlier elevations following intravitreal triamcinolone injections as compared to intravitreal dexamethasone implants. This review recommended that IOP be assessed every two weeks in the first month and monthly for an additional six months at a minimum.

Well-designed randomized controlled trials also support initial follow-up of no later than seven weeks. The Standard of Care vs. Corticosteroid for Retinal Vein Occlusion (SCORE) study where pressures peaked within 52.5 days following 4 mg intravitreal triamcinolone acetonide injection and the GENEVA study examining the effectiveness of dexamethasone intravitreal injections saw IOP peak within 60 days (Haller, 2010; Aref, 2015).

For patients with a diagnosis of glaucoma, these symptoms can occur earlier and we would expect the follow up timeframe would occur sooner such as within the first four weeks following the injection (Vie, 2017).

📋Implementation Notes

This measure contains one strata defined by a single submission criteria. This measure produces a single performance rate. For the purposes of MIPS implementation, this patient-process measure is submitted a minimum of once per patient during the performance period. The most advantageous quality data code will be used if the measure is submitted more than once.

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